Anti-HMOX2 antibody (1-270) (STJ24054)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal HMOX2 (1-270) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HMOX2 |
| Gene ID | 3163 |
| Uniprot ID | HMOX2_HUMAN |
| Immunogen Region | 1-270 |
| Immunogen Sequence | MSAEVETSEGVDESEKKNSG ALEKENQMRMADLSELLKEG TKEAHDRAENTQFVKDFLKG NIKKELFKLATTALYFTYSA LEEEMERNKDHPAFAPLYFP MELHRKEALTKDMEYFFGEN WEEQVQCPKAAQKYVERIHY IGQNEPELLVAHAYTRYMGD LSGGQVLKKVAQRALKLPST GEGTQFYLFENVDNAQQFKQ LYRARMNALDLNMKTKERIV EEANKAFEYNMQIFNELDQ |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human HMOX2 (NP_002125.3). |
Additional Info
| Post Translational Modifications | A soluble form arises by proteolytic removal of the membrane anchor. S-nitrosylated by BLVRB. |
| Function | Heme oxygenase 2: Catalyzes the oxidative cleavage of heme at the alpha-methene bridge carbon, released as carbon monoxide (CO), to generate biliverdin IXalpha, while releasing the central heme iron chelate as ferrous iron. Heme oxygenase 2 soluble form: Catalyzes the oxidative cleavage of heme at the alpha-methene bridge carbon, released as carbon monoxide (CO), to generate biliverdin IXalpha, while releasing the central heme iron chelate as ferrous iron. |
| Protein Name | Heme Oxygenase 2Ho-2 Cleaved Into - Heme Oxygenase 2 Soluble Form |
| Database Links | Reactome: R-HSA-189483Reactome: R-HSA-6798695Reactome: R-HSA-8980692Reactome: R-HSA-917937Reactome: R-HSA-9707564 |
| Cellular Localisation | Microsome MembraneSingle-Pass Type Iv Membrane ProteinCytoplasmic SideEndoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Heme Oxygenase 2 antibodyAnti-Ho-2 Cleaved Into - Heme Oxygenase 2 Soluble Form antibodyAnti-HMOX2 antibodyAnti-HO2 antibody |
Information sourced from Uniprot.org