Anti-HMMR antibody (280-340 aa) (STJ98724)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide from the human protein at the amino acid range 280-340
General Information
| Short Description | Rabbit polyclonal anti-Hyaluronan mediated motility receptor (280-340 aa) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:500-200ELISA 1:10000-20000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HMMR |
| Gene ID | 3161 |
| Uniprot ID | HMMR_HUMAN |
| Immunogen | Synthetic peptide from the human protein at the amino acid range 280-340 |
| Immunogen Region | 280-340 aa |
| Specificity | The antibody detects endogenous CD168 |
Additional Info
| Function | Receptor for hyaluronic acid (HA). Involved in cell motility. When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity. May act as a regulator of adipogenisis. |
| Protein Name | Hyaluronan Mediated Motility ReceptorIntracellular Hyaluronic Acid-Binding ProteinReceptor For Hyaluronan-Mediated MotilityCd Antigen Cd168 |
| Database Links | Reactome: R-HSA-2160916Reactome: R-HSA-8854518 |
| Cellular Localisation | Cell SurfaceCytoplasmCytoskeletonSpindle |
| Alternative Antibody Names | Anti-Hyaluronan Mediated Motility Receptor antibodyAnti-Intracellular Hyaluronic Acid-Binding Protein antibodyAnti-Receptor For Hyaluronan-Mediated Motility antibodyAnti-Cd Antigen Cd168 antibodyAnti-HMMR antibodyAnti-IHABP antibodyAnti-RHAMM antibody |
Information sourced from Uniprot.org