Anti-HMGN1 antibody (10-59 aa) (STJ93549)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human HMG14 at the amino acid range 10-59
General Information
| Short Description | Rabbit polyclonal anti-Non-histone chromosomal protein HMG-14 (10-59 aa) for use in IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC 1:100-1:300IF 1:200-1:1000ELISA 1:20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HMGN1 |
| Gene ID | 3150 |
| Uniprot ID | HMGN1_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human HMG14 at the amino acid range 10-59 |
| Immunogen Region | 10-59 aa |
| Specificity | HMG-14 Polyclonal Antibody detects endogenous levels of HMG-14 protein. |
Additional Info
| Function | Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation. Inhibits the phosphorylation of nucleosomal histones H3 and H2A by RPS6KA5/MSK1 and RPS6KA3/RSK2. |
| Protein Name | Non-Histone Chromosomal Protein Hmg-14High Mobility Group Nucleosome-Binding Domain-Containing Protein 1 |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmCytoplasmic Enrichment Upon PhosphorylationThe Rna Edited Version Localizes To The Nucleus |
| Alternative Antibody Names | Anti-Non-Histone Chromosomal Protein Hmg-14 antibodyAnti-High Mobility Group Nucleosome-Binding Domain-Containing Protein 1 antibodyAnti-HMGN1 antibodyAnti-HMG14 antibody |
Information sourced from Uniprot.org