• STJ72021 (1µg/ml) staining of Human Heart lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-HMGI-C/HMGA2 antibody (Internal) (STJ72021)

SKU:
STJ72021-100

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Host: Goat
Applications: Pep-ELISA/WB
Reactivity: Human/Dog
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-HMGI-C/HMGA2 (Internal) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: ELISA-antibody detection limit dilution 1:8000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: HMGA2
Gene ID: 8091
Uniprot ID: HMGA2_HUMAN
Immunogen Region: Internal
Accession Number: NP_003474.1; NP_003475.1
Specificity: This antibody is expected to recognize both reported isoforms (NP_003474.1; NP_003475.1) and is not expected to cross-react with HMGA1.
Immunogen Sequence: KAAQKKAEATGEK
Function Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. Plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes. Plays a role in postnatal myogenesis, is involved in satellite cell activation. Positively regulates IGF2 expression through PLAG1 and in a PLAG1-independent manner.
Protein Name High Mobility Group Protein Hmgi-C
High Mobility Group At-Hook Protein 2
Database Links Reactome: R-HSA-2559584
Cellular Localisation Nucleus
Alternative Antibody Names Anti-High Mobility Group Protein Hmgi-C antibody
Anti-High Mobility Group At-Hook Protein 2 antibody
Anti-HMGA2 antibody
Anti-HMGIC antibody

Information sourced from Uniprot.org

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