• STJ71997 (0. 5µg/ml) staining of Human Pancreas lysate (35µg protein in RIPA buffer) with (B) and without (A) blocking with the immunising peptide. Detected by chemiluminescence.

Anti-HMGA1 antibody (9-21) (STJ71997)

SKU:
STJ71997-100

£303.50
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Host: Goat
Applications: Pep-ELISA/WB/IHC
Reactivity: Human/Mouse/Rat/Dog/Cow/Pig
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-HMGA1 (9-21) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: IHC-3.75µg/ml
ELISA-antibody detection limit dilution 1:16000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: HMGA1
Gene ID: 3159
Uniprot ID: HMGA1_HUMAN
Immunogen Region: 9-21
Accession Number: NP_665906.1; NP_002122.1
Specificity: This antibody is expected to recognize reported isoforms a (NP_665906.1, NP_665908.1, NP_665911.1) and b (NP_002122.1, NP_665910.1, NP_665912.1). This antibody is not expected to cross-react with HMGA2.
Immunogen Sequence: SQPLASKQEKDGT
Function HMG-I/Y bind preferentially to the minor groove of A+T rich regions in double-stranded DNA. It is suggested that these proteins could function in nucleosome phasing and in the 3'-end processing of mRNA transcripts. They are also involved in the transcription regulation of genes containing, or in close proximity to A+T-rich regions.
Protein Name High Mobility Group Protein Hmg-I/Hmg-Y
Hmg-I(Y
High Mobility Group At-Hook Protein 1
High Mobility Group Protein A1
High Mobility Group Protein R
Database Links Reactome: R-HSA-162592
Reactome: R-HSA-164843
Reactome: R-HSA-175567
Reactome: R-HSA-177539
Reactome: R-HSA-180689
Reactome: R-HSA-180910
Reactome: R-HSA-2559584
Cellular Localisation Nucleus
Chromosome
Alternative Antibody Names Anti-High Mobility Group Protein Hmg-I/Hmg-Y antibody
Anti-Hmg-I(Y antibody
Anti-High Mobility Group At-Hook Protein 1 antibody
Anti-High Mobility Group Protein A1 antibody
Anti-High Mobility Group Protein R antibody
Anti-HMGA1 antibody
Anti-HMGIY antibody

Information sourced from Uniprot.org

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