Anti-HMG20A antibody (C-Term) (STJ70238)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-HMG20A (C-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/WB/IHC |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog/Pig/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:32000.WB: This antibody has been successfully used in Rat Brain as described in the following paper: Artegiani et al, J Biol Chem. 2010 Aug 6;285 (32) :24740-50.; PMID: 20530487.IHC: In par |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | HMG20A |
| Gene ID | 10363 |
| Uniprot ID | HM20A_HUMAN |
| Accession Number | NP_060670.1 |
| Immunogen Region | C-Term |
| Immunogen Sequence | ATVREVVNRLDR |
Additional Info
| Function | Plays a role in neuronal differentiation as chromatin-associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase KMT2A/MLL1 and consequent increased methylation of histone H3 lysine 4. |
| Protein Name | High Mobility Group Protein 20aHmg Box-Containing Protein 20aHmg Domain-Containing Protein 1Hmg Domain-Containing Protein Hmgx1 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-High Mobility Group Protein 20a antibodyAnti-Hmg Box-Containing Protein 20a antibodyAnti-Hmg Domain-Containing Protein 1 antibodyAnti-Hmg Domain-Containing Protein Hmgx1 antibodyAnti-HMG20A antibodyAnti-HMGX1 antibodyAnti-HMGXB1 antibody |
Information sourced from Uniprot.org