![Anti-HLA-DR1 antibody [MEM-267] (STJ16100939)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/149656/346899/STJ16100939_1__93804.1681999074.jpg?c=1 "Anti-HLA-DR1 antibody [MEM-267] (STJ16100939)")
![Anti-HLA-DR1 antibody [MEM-267] (STJ16100939)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/149656/346899/STJ16100939_1__93804.1681999074.jpg?c=1 "Anti-HLA-DR1 antibody [MEM-267] (STJ16100939)")
Anti-HLA-DR1 antibody [MEM-267] (STJ16100939)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2b
ImmunogenPurified, insoluble DR1 beta chain (DRB1*0101) expressed in E. coli inclusion bodies.
General Information
| Short Description | Mouse monoclonal anti-HLA-DR1 for use in WB, FC and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/FC/ELISA |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | MEM-267 |
| Isotype | IgG2b |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Formulation | Phosphate buffered saline (PBS) solution with 15 mM sodium azide |
| Storage Instruction | Store at 2-8°C for up to 1-year, upon receipt. |
Target Information
| Immunogen | Purified, insoluble DR1 beta chain (DRB1*0101) expressed in E. coli inclusion bodies. |
Additional Info
| Background | HLA-DR1 belongs to the HLA class II beta chain paralogues. The MHC Class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB) , both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. MHC Class II molecules are expressed in antigen presenting cells (APC). The beta chain is approximately 26-28 kDa. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Hundreds of DRB1 alleles have been described and typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. |
Information sourced from Uniprot.org