Anti-HKDC1 antibody (STJA0008022)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human HKDC1
General Information
| Short Description | Rabbit polyclonal anti-Hexokinase HKDC1 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HKDC1 |
| Gene ID | 80201 |
| Uniprot ID | HKDC1_HUMAN |
| Immunogen | Synthesized peptide derived from human HKDC1 |
| Specificity | This antibody detects endogenous levels of HKDC1 at Human, Mouse |
Additional Info
| Function | Catalyzes the phosphorylation of hexose to hexose 6-phosphate, although at very low level compared to other hexokinases. Has low glucose phosphorylating activity compared to other hexokinases. Involved in glucose homeostasis and hepatic lipid accumulation. Required to maintain whole-body glucose homeostasis during pregnancy.however additional evidences are required to confirm this role. |
| Protein Name | Hexokinase Hkdc1Hexokinase Domain-Containing Protein 1 |
| Database Links | Reactome: R-HSA-70171 |
| Cellular Localisation | CytoplasmMitochondrion MembranePeripheral Membrane ProteinPhotoreceptor Inner SegmentThe Mitochondrial-Binding Peptide (Mbp) Region Promotes Association With The Mitochondrion |
| Alternative Antibody Names | Anti-Hexokinase Hkdc1 antibodyAnti-Hexokinase Domain-Containing Protein 1 antibodyAnti-HKDC1 antibody |
Information sourced from Uniprot.org