Anti-HJURP antibody (80-160 aa) (STJ190300)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 80-160
General Information
| Short Description | Rabbit polyclonal anti-Holliday junction recognition protein (80-160 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HJURP |
| Gene ID | 55355 |
| Uniprot ID | HJURP_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 80-160 |
| Immunogen Region | 80-160 aa |
| Specificity | HJURP Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. Directly binds Holliday junctions. |
| Protein Name | Holliday Junction Recognition Protein14-3-3-Associated Akt SubstrateFetal Liver-Expressing Gene 1 ProteinUp-Regulated In Lung Cancer 9 |
| Database Links | Reactome: R-HSA-606279 |
| Cellular Localisation | NucleusNucleolusChromosomeCentromereLocalizes In Centromeres During Late Telophase And Early G1When Cenpa Nucleosomes Are AssembledLocalizes To Nucleolus During S PhaseNucleolus Site Being Often Related To Storage |
| Alternative Antibody Names | Anti-Holliday Junction Recognition Protein antibodyAnti-14-3-3-Associated Akt Substrate antibodyAnti-Fetal Liver-Expressing Gene 1 Protein antibodyAnti-Up-Regulated In Lung Cancer 9 antibodyAnti-HJURP antibodyAnti-FAKTS antibodyAnti-FLEG1 antibodyAnti-URLC9 antibody |
Information sourced from Uniprot.org