Anti-Histone H3.2 antibody (81-131 aa) (STJ194163)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human H32 at the amino acid range 81-131
General Information
| Short Description | Rabbit polyclonal anti-Histone H3.2 (81-131 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | H3C15.H3C14.H3C13 |
| Gene ID | 126961/333932/653604 |
| Uniprot ID | H32_HUMAN |
| Immunogen | Synthesized peptide derived from the human H32 at the amino acid range 81-131 |
| Immunogen Region | 81-131 aa |
| Specificity | This antibody detects endogenous levels of H32 at Human/Mouse |
Additional Info
| Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| Protein Name | Histone H3.2H3-Clustered Histone 13H3-Clustered Histone 14H3-Clustered Histone 15Histone H3/MHistone H3/O |
| Database Links | Reactome: R-HSA-1266695Reactome: R-HSA-1912408Reactome: R-HSA-201722Reactome: R-HSA-212300Reactome: R-HSA-2299718Reactome: R-HSA-2559580Reactome: R-HSA-2559582Reactome: R-HSA-3214815Reactome: R-HSA-3214841Reactome: R-HSA-3214842Reactome: R-HSA-3214847Reactome: R-HSA-3214858Reactome: R-HSA-3247509Reactome: R-HSA-427359Reactome: R-HSA-427389Reactome: R-HSA-427413Reactome: R-HSA-5250924Reactome: R-HSA-5334118Reactome: R-HSA-5578749Reactome: R-HSA-5617472Reactome: R-HSA-5625886Reactome: R-HSA-68616Reactome: R-HSA-73728Reactome: R-HSA-73772Reactome: R-HSA-8936459Reactome: R-HSA-8939236Reactome: R-HSA-9018519Reactome: R-HSA-912446Reactome: R-HSA-9609690Reactome: R-HSA-9610379Reactome: R-HSA-9616222Reactome: R-HSA-9710421Reactome: R-HSA-977225Reactome: R-HSA-9821002Reactome: R-HSA-983231Reactome: R-HSA-9841922Reactome: R-HSA-9843940Reactome: R-HSA-9843970Reactome: R-HSA-9845323 |
| Cellular Localisation | NucleusChromosome |
| Alternative Antibody Names | Anti-Histone H3.2 antibodyAnti-H3-Clustered Histone 13 antibodyAnti-H3-Clustered Histone 14 antibodyAnti-H3-Clustered Histone 15 antibodyAnti-Histone H3/M antibodyAnti-Histone H3/O antibodyAnti-H3C15 antibodyAnti-HIST2H3A.H3C14 antibodyAnti-H3F2 antibodyAnti-H3FM antibodyAnti-HIST2H3C.H3C13 antibodyAnti-HIST2H3D antibody |
Information sourced from Uniprot.org