Anti-Histone H1.0 antibody [R07-0E8] (STJA0034409)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human Histone H1.0
General Information
| Short Description | Rabbit monoclonal anti-Histone H1.0 for use in WB and IHC-P in Human, Rat and Hamster samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P |
| Host | Rabbit |
| Reactivity | Human/Rat/Hamster |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R07-0E8 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | H1-0 |
| Gene ID | 3005 |
| Uniprot ID | H10_HUMAN |
| Immunogen | A synthetic peptide of human Histone H1.0 |
Additional Info
| Post Translational Modifications | Phosphorylated on Ser-17 in RNA edited version. ADP-ribosylated on Ser-104 in response to DNA damage. |
| Function | Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. The histones H1.0 are found in cells that are in terminal stages of differentiation or that have low rates of cell division. |
| Protein Name | Histone H1.0Histone H1'Histone H1(0 Cleaved Into - Histone H1.0 - N-Terminally Processed |
| Database Links | Reactome: R-HSA-140342Reactome: R-HSA-2559584 |
| Cellular Localisation | NucleusChromosomeThe Rna Edited Version Has Been Localized To Nuclear SpecklesDuring MitosisIt Appears In The Vicinity Of Condensed Chromosomes |
| Alternative Antibody Names | Anti-Histone H1.0 antibodyAnti-Histone H1' antibodyAnti-Histone H1(0 Cleaved Into - Histone H1.0 - N-Terminally Processed antibodyAnti-H1-0 antibodyAnti-H1F0 antibodyAnti-H1FV antibody |
Information sourced from Uniprot.org