Anti-histamine H3 receptor antibody (Internal) (STJ72900)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-histamine H3 receptor (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/WB/IHC |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Approx 48kDa band observed in lysates of cell line A549 (calculated MW of 48.7kDa according to NP_009163.2). Recommended concentration: 0.1-0.3ยตg/ml. Primary incubation was 1 hour. |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20ยฐC on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | HRH3 |
| Gene ID | 11255 |
| Uniprot ID | HRH3_HUMAN |
| Accession Number | NP_009163.2 |
| Immunogen Region | Internal |
| Immunogen Sequence | SVTRAVSYRAQQGDT |
Additional Info
| Function | The H3 subclass of histamine receptors could mediate the histamine signals in CNS and peripheral nervous system. Signals through the inhibition of adenylate cyclase and displays high constitutive activity (spontaneous activity in the absence of agonist). Agonist stimulation of isoform 3 neither modified adenylate cyclase activity nor induced intracellular calcium mobilization. |
| Protein Name | Histamine H3 ReceptorH3rHh3rG-Protein Coupled Receptor 97 |
| Database Links | Reactome: R-HSA-390650 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Histamine H3 Receptor antibodyAnti-H3r antibodyAnti-Hh3r antibodyAnti-G-Protein Coupled Receptor 97 antibodyAnti-HRH3 antibodyAnti-GPCR97 antibody |
Information sourced from Uniprot.org