Anti-HIP1R/HIP12 antibody (C-Term) (STJ71840)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-HIP1R/HIP12 (C-Term) is suitable for use in ELISA research applications. |
| Applications | Pep-ELISA |
| Host | Goat |
| Reactivity | Human/Dog/Cow/Pig |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Preliminary experiments in Human Brain (Amygdala, Hippocampus and Substantia nigra) lysates gave no specific signal but low background (at antibody concentration up to 1ยตg/ml). We woul |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20ยฐC on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | HIP1R |
| Gene ID | 9026 |
| Uniprot ID | HIP1R_HUMAN |
| Accession Number | NP_003950.1 |
| Immunogen Region | C-Term |
| Immunogen Sequence | RQDHQLDKKDGIYP |
Additional Info
| Function | Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis. |
| Protein Name | Huntingtin-Interacting Protein 1-Related ProteinHip1-Related ProteinHuntingtin-Interacting Protein 12Hip-12 |
| Database Links | Reactome: R-HSA-432722Reactome: R-HSA-8856828 |
| Cellular Localisation | CytoplasmPerinuclear RegionEndomembrane SystemCytoplasmic VesicleClathrin-Coated Vesicle MembraneMembrane-Associated ProteinMainly Localized At The Endocytic Compartments And In The Perinuclear Region |
| Alternative Antibody Names | Anti-Huntingtin-Interacting Protein 1-Related Protein antibodyAnti-Hip1-Related Protein antibodyAnti-Huntingtin-Interacting Protein 12 antibodyAnti-Hip-12 antibodyAnti-HIP1R antibodyAnti-HIP12 antibodyAnti-KIAA0655 antibody |
Information sourced from Uniprot.org