Anti-HINT2 antibody (18-163aa) [AT5B10] (STJA0041753)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1k
ImmunogenRecombinant human HINT2 (18-163aa) purified from E. coli
General Information
| Short Description | Mouse monoclonal anti-HINT2 (18-163aa) for use in ELISA and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/WB |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | AT5B10 |
| Isotype | IgG1k |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | By protein-A affinity chromatography |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HINT2 |
| Gene ID | 84681 |
| Uniprot ID | HINT2_HUMAN |
| Accession Number | NP_115982 |
| Immunogen | Recombinant human HINT2 (18-163aa) purified from E. coli |
| Immunogen Region | 18-163aa |
Additional Info
| Tissue Specificity | High expression in liver and pancreas. Expression is significantly down-regulated in hepatocellular carcinoma (HCC) patients. |
| Function | Exhibits adenosine 5'-monophosphoramidase activity, hydrolyzing purine nucleotide phosphoramidates with a single phosphate group such as adenosine 5'monophosphoramidate (AMP-NH2) to yield AMP and NH2. Hydrolyzes adenosine 5'-O-p-nitrophenylphosphoramidate (AMP-pNA). Hydrolyzes fluorogenic purine nucleoside tryptamine phosphoramidates in vitro. May be involved in steroid biosynthesis. May play a role in apoptosis. |
| Protein Name | Adenosine 5'-Monophosphoramidase Hint2Hint-3Hit-17kdaHistidine Triad Nucleotide-Binding Protein 2 - MitochondrialHint-2Pkci-1-Related Hit Protein |
| Database Links | Reactome: R-HSA-9013405 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Adenosine 5'-Monophosphoramidase Hint2 antibodyAnti-Hint-3 antibodyAnti-Hit-17kda antibodyAnti-Histidine Triad Nucleotide-Binding Protein 2 - Mitochondrial antibodyAnti-Hint-2 antibodyAnti-Pkci-1-Related Hit Protein antibodyAnti-HINT2 antibody |
Information sourced from Uniprot.org