Anti-HFE antibody [R66-6Q-3] (STJA0035535)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human HFE
General Information
| Short Description | Rabbit monoclonal anti-HFE for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R66-6Q-3 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000 |
| Formulation | Liquid in PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | HFE |
| Gene ID | 3077 |
| Uniprot ID | HFE_HUMAN |
| Immunogen | A synthesized peptide derived from human HFE |
Additional Info
| Tissue Specificity | Expressed in all tissues tested except brain. |
| Function | Binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin. |
| Protein Name | Hereditary Hemochromatosis ProteinHla-H |
| Database Links | Reactome: R-HSA-917977 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Hereditary Hemochromatosis Protein antibodyAnti-Hla-H antibodyAnti-HFE antibodyAnti-HLAH antibody |
Information sourced from Uniprot.org