| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-HFE (80-306) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
HFE |
| Gene ID: |
3077 |
| Uniprot ID: |
HFE_HUMAN |
| Immunogen Region: |
80-306 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 80-306 of human HFE (NP_000401.1). |
| Immunogen Sequence: |
SSQMWLQLSQSLKGWDHMFT VDFWTIMENHNHSKESHTLQ VILGCEMQEDNSTEGYWKYG YDGQDHLEFCPDTLDWRAAE PRAWPTKLEWERHKIRARQN RAYLERDCPAQLQQLLELGR GVLDQQVPPLVKVTHHVTSS VTTLRCRALNYYPQNITMKW LKDKQPMDAKEFEPKDVLPN GDGTYQGWITLAVPPGEEQR YTCQVEHPGLDQPLIVIWEP SPSGTLV |
| Tissue Specificity | Expressed in all tissues tested except brain. |
| Function | Binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin. |
| Protein Name | Hereditary Hemochromatosis ProteinHla-H |
| Database Links | Reactome: R-HSA-917977 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Hereditary Hemochromatosis Protein antibodyAnti-Hla-H antibodyAnti-HFE antibodyAnti-HLAH antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
