Anti-HEXA antibody (121-170 aa) (STJ96598)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from HEXA at the amino acid range 121-170
General Information
| Short Description | Rabbit polyclonal anti-Beta-hexosaminidase subunit alpha (121-170 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC-P 1:100-300ELISA 1:20000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HEXA |
| Gene ID | 3073 |
| Uniprot ID | HEXA_HUMAN |
| Immunogen | Synthesized peptide derived from HEXA at the amino acid range 121-170 |
| Immunogen Region | 121-170 aa |
| Specificity | HEXA Polyclonal Antibody detects endogenous levels of HEXA protein. |
Additional Info
| Function | Hydrolyzes the non-reducing end N-acetyl-D-hexosamine and/or sulfated N-acetyl-D-hexosamine of glycoconjugates, such as the oligosaccharide moieties from proteins and neutral glycolipids, or from certain mucopolysaccharides. The isozyme S is as active as the isozyme A on the anionic bis-sulfated glycans, the chondroitin-6-sulfate trisaccharide (C6S-3), and the dermatan sulfate pentasaccharide, and the sulfated glycosphingolipid SM2. The isozyme B does not hydrolyze each of these substrates, however hydrolyzes efficiently neutral oligosaccharide. Only the isozyme A is responsible for the degradation of GM2 gangliosides in the presence of GM2A. |
| Protein Name | Beta-Hexosaminidase Subunit AlphaBeta-N-Acetylhexosaminidase Subunit AlphaHexosaminidase Subunit AN-Acetyl-Beta-Glucosaminidase Subunit Alpha |
| Database Links | Reactome: R-HSA-2022857Reactome: R-HSA-2024101Reactome: R-HSA-2160916Reactome: R-HSA-3656234Reactome: R-HSA-9840310 |
| Cellular Localisation | Lysosome |
| Alternative Antibody Names | Anti-Beta-Hexosaminidase Subunit Alpha antibodyAnti-Beta-N-Acetylhexosaminidase Subunit Alpha antibodyAnti-Hexosaminidase Subunit A antibodyAnti-N-Acetyl-Beta-Glucosaminidase Subunit Alpha antibodyAnti-HEXA antibody |
Information sourced from Uniprot.org