Host: |
Rabbit |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Beta-hexosaminidase subunit alpha (121-170 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IHC-P 1:100-300ELISA 1:20000IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
HEXA |
Gene ID: |
3073 |
Uniprot ID: |
HEXA_HUMAN |
Immunogen Region: |
121-170 aa |
Specificity: |
HEXA Polyclonal Antibody detects endogenous levels of HEXA protein. |
Immunogen: |
Synthesized peptide derived from HEXA at the amino acid range 121-170 |
Function | Hydrolyzes the non-reducing end N-acetyl-D-hexosamine and/or sulfated N-acetyl-D-hexosamine of glycoconjugates, such as the oligosaccharide moieties from proteins and neutral glycolipids, or from certain mucopolysaccharides. The isozyme S is as active as the isozyme A on the anionic bis-sulfated glycans, the chondroitin-6-sulfate trisaccharide (C6S-3), and the dermatan sulfate pentasaccharide, and the sulfated glycosphingolipid SM2. The isozyme B does not hydrolyze each of these substrates, however hydrolyzes efficiently neutral oligosaccharide. Only the isozyme A is responsible for the degradation of GM2 gangliosides in the presence of GM2A. |
Protein Name | Beta-Hexosaminidase Subunit AlphaBeta-N-Acetylhexosaminidase Subunit AlphaHexosaminidase Subunit AN-Acetyl-Beta-Glucosaminidase Subunit Alpha |
Database Links | Reactome: R-HSA-1660662Reactome: R-HSA-2022857Reactome: R-HSA-2024101Reactome: R-HSA-2160916Reactome: R-HSA-3656234 |
Cellular Localisation | Lysosome |
Alternative Antibody Names | Anti-Beta-Hexosaminidase Subunit Alpha antibodyAnti-Beta-N-Acetylhexosaminidase Subunit Alpha antibodyAnti-Hexosaminidase Subunit A antibodyAnti-N-Acetyl-Beta-Glucosaminidase Subunit Alpha antibodyAnti-HEXA antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance