| Short Description : | Rabbit monoclonal Hex (50-150) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S2MR |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HHEX |
| Gene ID: | 3087 |
| Uniprot ID: | HHEX_HUMAN |
| Immunogen Region: | 50-150 |
| Immunogen Sequence: | TLPSPNSSFTSLVSPYRTPV YEPTPIHPAFSHHSAAALAA AYGPGGFGGPLYPFPRTVND YTHALLRHDPLGKPLLWSPF LQRPLHKRKGGQVRFSNDQT I |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human Hex (Q03014). |
| Tissue Specificity | Liver and promyelocytic leukemia cell line HL-60. |
| Function | Recognizes the DNA sequence 5'-ATTAA-3'. Transcriptional repressor. Activator of WNT-mediated transcription in conjunction with CTNNB1. Establishes anterior identity at two levels.acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL. Inhibits EIF4E-mediated mRNA nuclear export. May play a role in hematopoietic differentiation. |
| Protein Name | Hematopoietically-Expressed Homeobox Protein HhexHomeobox Protein HexHomeobox Protein PrhProline-Rich Homeodomain Protein |
| Database Links | Reactome: R-HSA-9925561 |
| Cellular Localisation | NucleusNuclear BodyCytoplasm |
| Alternative Antibody Names | Anti-Hematopoietically-Expressed Homeobox Protein Hhex antibodyAnti-Homeobox Protein Hex antibodyAnti-Homeobox Protein Prh antibodyAnti-Proline-Rich Homeodomain Protein antibodyAnti-HHEX antibodyAnti-HEX antibodyAnti-PRH antibodyAnti-PRHX antibody |
Information sourced from Uniprot.org
