Anti-Hex antibody [R04-3D2] (STJA0035026)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human Hex
General Information
| Short Description | Rabbit monoclonal anti-Hex for use in WB and IP in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IP |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R04-3D2 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IP 1:20 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | HHEX |
| Gene ID | 3087 |
| Uniprot ID | HHEX_HUMAN |
| Immunogen | A synthetic peptide of human Hex |
Additional Info
| Tissue Specificity | Liver and promyelocytic leukemia cell line HL-60. |
| Function | Recognizes the DNA sequence 5'-ATTAA-3'. Transcriptional repressor. Activator of WNT-mediated transcription in conjunction with CTNNB1. Establishes anterior identity at two levels.acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL. Inhibits EIF4E-mediated mRNA nuclear export. May play a role in hematopoietic differentiation. |
| Protein Name | Hematopoietically-Expressed Homeobox Protein HhexHomeobox Protein HexHomeobox Protein PrhProline-Rich Homeodomain Protein |
| Database Links | Reactome: R-HSA-9925561 |
| Cellular Localisation | NucleusNuclear BodyCytoplasm |
| Alternative Antibody Names | Anti-Hematopoietically-Expressed Homeobox Protein Hhex antibodyAnti-Homeobox Protein Hex antibodyAnti-Homeobox Protein Prh antibodyAnti-Proline-Rich Homeodomain Protein antibodyAnti-HHEX antibodyAnti-HEX antibodyAnti-PRH antibodyAnti-PRHX antibody |
Information sourced from Uniprot.org