Anti-HERC4 antibody (STJA0008333)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human HERC4
General Information
| Short Description | Rabbit polyclonal anti-Probable E3 ubiquitin-protein ligase HERC4 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HERC4 |
| Gene ID | 26091 |
| Uniprot ID | HERC4_HUMAN |
| Immunogen | Synthesized peptide derived from human HERC4 |
| Specificity | This antibody detects endogenous levels of HERC4 at Human, Mouse, Rat |
Additional Info
| Function | Probable E3 ubiquitin-protein ligase involved in either protein trafficking or in the distribution of cellular structures. Required for spermatozoon maturation and fertility, and for the removal of the cytoplasmic droplet of the spermatozoon. E3 ubiquitin-protein ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer it to targeted substrates. |
| Protein Name | Probable E3 Ubiquitin-Protein Ligase Herc4Hect Domain And Rcc1-Like Domain-Containing Protein 4Hect-Type E3 Ubiquitin Transferase Herc4 |
| Database Links | Reactome: R-HSA-983168 |
| Cellular Localisation | CytoplasmCytosolShows A Punctate Cytoplasmic Distribution |
| Alternative Antibody Names | Anti-Probable E3 Ubiquitin-Protein Ligase Herc4 antibodyAnti-Hect Domain And Rcc1-Like Domain-Containing Protein 4 antibodyAnti-Hect-Type E3 Ubiquitin Transferase Herc4 antibodyAnti-HERC4 antibodyAnti-KIAA1593 antibody |
Information sourced from Uniprot.org