Anti-HERC3 antibody (1-200) (STJ111302)

Name: Anti-HERC3 antibody (1-200) (STJ111302)
SKU: STJ111302
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ111302

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Short Description	Rabbit polyclonal HERC3 (1-200) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Human/Mouse
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	HERC3
Gene ID	8916
Uniprot ID	HERC3_HUMAN
Immunogen Region	1-200
Immunogen Sequence	MLCWGYWSLGQPGISTNLQG IVAEPQVCGFISDRSVKEVA CGGNHSVFLLEDGEVYTCGL NTKGQLGHEREGNKPEQIGA LADQHIIHVACGESHSLALS DRGQLFSWGAGSDGQLGLMT TEDSVAVPRLIQKLNQQTIL QVSCGNWHCLALAADGQFFT WGKNSHGQLGLGKEFPSQAS PQRVRSLEGIPLAQVAAGGA
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human HERC3 (NP_055421.1).

Post Translational Modifications	Ubiquitinated.which promotes degradation by the proteasome.
Function	E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
Protein Name	Probable E3 Ubiquitin-Protein Ligase Herc3 Hect Domain And Rcc1-Like Domain-Containing Protein 3 Hect-Type E3 Ubiquitin Transferase Herc3
Database Links	Reactome: R-HSA-983168
Cellular Localisation	Cytoplasm Cytoplasmic Vesicle Also Found In Vesicular-Like Structures
Alternative Antibody Names	Anti-Probable E3 Ubiquitin-Protein Ligase Herc3 antibody Anti-Hect Domain And Rcc1-Like Domain-Containing Protein 3 antibody Anti-Hect-Type E3 Ubiquitin Transferase Herc3 antibody Anti-HERC3 antibody Anti-KIAA0032 antibody

Information sourced from Uniprot.org