Anti-Her3 antibody [IHC113] (STJA0042186)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
General Information
| Short Description | Mouse monoclonal anti-Her3 for use in IHC-p in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-p |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | IHC113 |
| Conjugation | Unconjugated |
| Formulation | Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide |
| Storage Instruction | Store at 2-8°C for up to 1 year. Do not freeze. |
Target Information
| Specificity | Tested and validated on breast cancer tissue. |
Additional Info
| Background | Receptor tyrosine-protein kinase erbB-3, also known as HER-3 (Human Epidermal Growth Factor Receptor 3) , is a membrane bound protein and has been shown to bind the ligands heregulin and NRG-2. During human development, HER-3 antibody is expressed in skin, bone, muscle, nervous system, heart, lungs, and intestinal epithelium and is expressed in normal adult human gastrointestinal tract, reproductive system, skin, nervous system, urinary tract, and endocrine system. HER-3 is overexpressed in a variety of tumors including breast, stomach, pancreas, and colon, and is a reliable marker for aiding in the diagnosis of various cancers by immunohistochemistry. |
Information sourced from Uniprot.org