Anti-Her2/Neu antibody [IHC042] (STJA0042045)

SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
STJA0042045
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General Information

Short DescriptionMouse monoclonal anti-Her2/Neu for use in IHC-p in Human samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsIHC-p
HostMouse
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDIHC042
IsotypeIgG2a
ConjugationUnconjugated
Dilution Range1:50-1:200
FormulationTris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Storage InstructionStore at 2-8°C for up to 1 year. Do not freeze.

Target Information

SpecificityTested and validated on breast carcinoma tissue.

Additional Info

Background The HER2/neu (c-erbB-2) proto-oncogene is a transmembrane receptor tyrosine kinase that is clinically indicated in a number on carcinomas. Overexpression on the c-erbB-2 protein has been associated with ductal breast cancer, as well as pulmonary and gastric adenocarcinomas. A correlation between HER2 and p53 has also been documented, as overexpression on both proteins has been associated with early invasion and metastasis in bladder cancer.

Information sourced from Uniprot.org

Citations

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