Anti-Heme Oxygenase 1 antibody [SM4916] (STJA0004916)

SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG
ImmunogenKLH conjugated Synthetic peptide corresponding to Mouse HMOX1
STJA0004916
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General Information

Short DescriptionMouse monoclonal anti-Heme Oxygenase 1 for use in WB, IHC and IF in Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/IHC/IF
HostMouse
ReactivityMouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDSM4916
IsotypeIgG
ConjugationUnconjugated
PurificationAffinity purification
Dilution RangeWB (M, R) 1:500-1:1000
IHC/IF (M, R) 1:1000-1:2000/1:500-1:2000
FormulationPBS with 0.02% sodium azide, 100 Mu g/ml BSA and 50% glycerol.
Storage InstructionStore at-20C for up to one year, and avoid repeated freeze-thaw cycles.

Target Information

Gene SymbolHmox1
Gene ID15368
Uniprot IDHMOX1_MOUSE
ImmunogenKLH conjugated Synthetic peptide corresponding to Mouse HMOX1

Additional Info

Function Heme oxygenase 1: Catalyzes the oxidative cleavage of heme at the alpha-methene bridge carbon, released as carbon monoxide (CO), to generate biliverdin IXalpha, while releasing the central heme iron chelate as ferrous iron Affords protection against programmed cell death and this cytoprotective effect relies on its ability to catabolize free heme and prevent it from sensitizing cells to undergo apoptosis. Heme oxygenase 1 soluble form: Catalyzes the oxidative cleavage of heme at the alpha-methene bridge carbon, released as carbon monoxide (CO), to generate biliverdin IXalpha, while releasing the central heme iron chelate as ferrous iron.
Protein Name Heme Oxygenase 1
Ho-1
P32 Protein Cleaved Into - Heme Oxygenase 1 Soluble Form
Database Links Reactome: R-MMU-189483
Reactome: -MMU-917937
Reactome: -MMU-9609523
Reactome: -MMU-9707564
Reactome: -MMU-9707587
Cellular Localisation Endoplasmic Reticulum Membrane
Single-Pass Type Iv Membrane Protein
Cytoplasmic Side
Alternative Antibody Names Anti-Heme Oxygenase 1 antibody
Anti-Ho-1 antibody
Anti-P32 Protein Cleaved Into - Heme Oxygenase 1 Soluble Form antibody
Anti-Hmox1 antibody

Information sourced from Uniprot.org

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