Anti-HDGF antibody [SAA1795] (STJA0020223)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
General Information
| Short Description | Mouse monoclonal Hepatoma-Derived Growth Factor antibody for use in ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA1795 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Protein A/G purified from cell culture supernatant |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months |
Target Information
| Gene Symbol | HDGF |
| Gene ID | 3068 |
| Uniprot ID | HDGF_HUMAN |
Additional Info
| Post Translational Modifications | Sumoylated with SUMO1. Sumoylation prevents binding to chromatin. Phosphorylation at Ser-165 is likely to be required for secretion. |
| Function | Isoform 1: Acts as a transcriptional repressor. Has mitogenic activity for fibroblasts. Heparin-binding protein. Isoform 2: Does not have mitogenic activity for fibroblasts. Does not bind heparin. Isoform 3: Has mitogenic activity for fibroblasts. Heparin-binding protein. |
| Protein Name | Hepatoma-Derived Growth FactorHdgfHigh Mobility Group Protein 1-Like 2Hmg-1l2 |
| Database Links | Reactome: R-HSA-381038 |
| Cellular Localisation | Isoform 1: NucleusCytoplasmSecretedExtracellular ExosomeSecreted By Exosomes And Is Located Inside The ExosomeMay Also Be Secreted As Free Protein Via An As Yet Unknown PathwayIsoform 2: NucleusSecreted By Exosomes And Is Located On The Outer Exosome SurfaceIsoform 3: Nucleus |
| Alternative Antibody Names | Anti-Hepatoma-Derived Growth Factor antibodyAnti-Hdgf antibodyAnti-High Mobility Group Protein 1-Like 2 antibodyAnti-Hmg-1l2 antibodyAnti-HDGF antibodyAnti-HMG1L2 antibody |
Information sourced from Uniprot.org