Anti-HDAC11 antibody [R05-4K8] (STJA0035745)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human HDAC11
General Information
| Short Description | Rabbit monoclonal anti-HDAC11 for use in WB and IP in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IP |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R05-4K8 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000IP 1:50 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | HDAC11 |
| Gene ID | 79885 |
| Uniprot ID | HDA11_HUMAN |
| Immunogen | A synthesized peptide derived from human HDAC11 |
Additional Info
| Tissue Specificity | Weakly expressed in most tissues. Strongly expressed in brain, heart, skeletal muscle, kidney and testis. |
| Function | Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. |
| Protein Name | Histone Deacetylase 11Hd11 |
| Database Links | Reactome: R-HSA-2122947Reactome: R-HSA-2644606Reactome: R-HSA-2894862Reactome: R-HSA-350054 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Histone Deacetylase 11 antibodyAnti-Hd11 antibodyAnti-HDAC11 antibody |
Information sourced from Uniprot.org