| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Heart-and neural crest derivatives-expressed protein 2 is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
HAND2 |
| Gene ID: |
9464 |
| Uniprot ID: |
HAND2_HUMAN |
| Specificity: |
HAND2 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: |
Synthesized peptide derived from part of the human protein |
| Function | Essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. Required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. Also plays an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Is involved in the development of branchial arches, which give rise to unique structures in the head and neck. Binds DNA on E-box consensus sequence 5'-CANNTG-3'. |
| Protein Name | Heart- And Neural Crest Derivatives-Expressed Protein 2Class A Basic Helix-Loop-Helix Protein 26Bhlha26Deciduum - Heart - Autonomic Nervous System And Neural Crest Derivatives-Expressed Protein 2Dhand |
| Database Links | Reactome: R-HSA-8878166Reactome: R-HSA-9733709 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Heart- And Neural Crest Derivatives-Expressed Protein 2 antibodyAnti-Class A Basic Helix-Loop-Helix Protein 26 antibodyAnti-Bhlha26 antibodyAnti-Deciduum - Heart - Autonomic Nervous System And Neural Crest Derivatives-Expressed Protein 2 antibodyAnti-Dhand antibodyAnti-HAND2 antibodyAnti-BHLHA26 antibodyAnti-DHAND antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
