Anti-HAND2 antibody (1-100) {Biotin} (STJ501311)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationBiotin
IsotypeIgG
ImmunogenSynthetic peptide taken within amino acid region 1-100 on Human HAND2 protein.
General Information
| Short Description | Rabbit polyclonal antibody anti-HAND2 (1-100) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Applications | ELISA/IHC/IP/WB |
| Host | Rabbit |
| Reactivity | Human/Monkey/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Biotin |
| Concentration | 0.53-0.63 µg/µl |
| Purification | Affinity Purified |
| Dilution Range | WB: 1:500DB: 1:10, 000ELISA: 1:10, 000IP: 1:200IHC: 1:100 |
| Formulation | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | Hand2 |
| Gene ID | 64637 |
| Uniprot ID | HAND2_RAT |
| Immunogen | Synthetic peptide taken within amino acid region 1-100 on Human HAND2 protein. |
| Immunogen Region | 1-100 |
Additional Info
| Function | Essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. Required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. Also plays an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Is involved in the development of branchial arches, which give rise to unique structures in the head and neck. Binds DNA on E-box consensus sequence 5'-CANNTG-3'. |
| Protein Name | Heart- And Neural Crest Derivatives-Expressed Protein 2Deciduum - Heart - Autonomic Nervous System And Neural Crest Derivatives-Expressed Protein 2Dhand |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Heart- And Neural Crest Derivatives-Expressed Protein 2 antibodyAnti-Deciduum - Heart - Autonomic Nervous System And Neural Crest Derivatives-Expressed Protein 2 antibodyAnti-Dhand antibodyAnti-Hand2 antibodyAnti-Dhand antibody |
Information sourced from Uniprot.org