| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Hepcidin is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
HAMP |
| Gene ID: |
57817 |
| Uniprot ID: |
HEPC_HUMAN |
| Specificity: |
This antibody detects endogenous levels of Hepcidin-25 at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human Hepcidin-25 |
| Function | Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. Acts by promoting endocytosis and degradation of ferroportin/SLC40A1, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma. Controls the major flows of iron into plasma: absorption of dietary iron in the intestine, recycling of iron by macrophages, which phagocytose old erythrocytes and other cells, and mobilization of stored iron from hepatocytes. Has strong antimicrobial activity against E.coli ML35P N.cinerea and weaker against S.epidermidis, S.aureus and group b streptococcus bacteria. Active against the fungus C.albicans. No activity against P.aeruginosa. |
| Protein Name | HepcidinLiver-Expressed Antimicrobial Peptide 1Leap-1Putative Liver Tumor RegressorPltr Cleaved Into - Hepcidin-25Hepc25 - Hepcidin-20Hepc20 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Hepcidin antibodyAnti-Liver-Expressed Antimicrobial Peptide 1 antibodyAnti-Leap-1 antibodyAnti-Putative Liver Tumor Regressor antibodyAnti-Pltr Cleaved Into - Hepcidin-25 antibodyAnti-Hepc25 - Hepcidin-20 antibodyAnti-Hepc20 antibodyAnti-HAMP antibodyAnti-HEPC antibodyAnti-LEAP1 antibodyAnti-UNQ487 antibodyAnti-PRO1003 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
