Anti-HADHB antibody [SRM14808] (STJ11109538)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
General Information
| Short Description | Rabbit monoclonal HADHB antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SRM14808 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity purification |
| Dilution Range | WB, 1:5000-1:20000IHC-P, 1:200-1:2000IF/ICC, 1:200-1:2000ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HADHB |
| Gene ID | 3032 |
| Uniprot ID | ECHB_HUMAN |
| Immunogen | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
Additional Info
| Function | Mitochondrial trifunctional enzyme catalyzes the last three of the four reactions of the mitochondrial beta-oxidation pathway. The mitochondrial beta-oxidation pathway is the major energy-producing process in tissues and is performed through four consecutive reactions breaking down fatty acids into acetyl-CoA. Among the enzymes involved in this pathway, the trifunctional enzyme exhibits specificity for long-chain fatty acids. Mitochondrial trifunctional enzyme is a heterotetrameric complex composed of two proteins, the trifunctional enzyme subunit alpha/HADHA carries the 2,3-enoyl-CoA hydratase and the 3-hydroxyacyl-CoA dehydrogenase activities, while the trifunctional enzyme subunit beta/HADHB described here bears the 3-ketoacyl-CoA thiolase activity. |
| Protein Name | Trifunctional Enzyme Subunit Beta - MitochondrialTp-Beta Includes - 3-Ketoacyl-Coa ThiolaseAcetyl-Coa AcyltransferaseBeta-Ketothiolase |
| Database Links | Reactome: R-HSA-1482798Reactome: R-HSA-77285Reactome: R-HSA-77288Reactome: R-HSA-77305Reactome: R-HSA-77310Reactome: R-HSA-77346Reactome: R-HSA-77348Reactome: R-HSA-77350 |
| Cellular Localisation | MitochondrionMitochondrion Inner MembraneMitochondrion Outer MembraneEndoplasmic ReticulumProtein Stability And Association With Membranes Require Hadha |
| Alternative Antibody Names | Anti-Trifunctional Enzyme Subunit Beta - Mitochondrial antibodyAnti-Tp-Beta Includes - 3-Ketoacyl-Coa Thiolase antibodyAnti-Acetyl-Coa Acyltransferase antibodyAnti-Beta-Ketothiolase antibodyAnti-HADHB antibodyAnti-MSTP029 antibody |
Information sourced from Uniprot.org