| Host: |
Goat |
| Applications: |
Pep-ELISA/WB |
| Reactivity: |
Human/Mouse/Rat/Dog |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-HADH/HADHSC (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
ELISA-antibody detection limit dilution 1:64000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
HADH |
| Gene ID: |
3033 |
| Uniprot ID: |
HCDH_HUMAN |
| Immunogen Region: |
Internal |
| Accession Number: |
NP_005318.2 |
| Immunogen Sequence: |
YERGDASKEDID |
| Post Translational Modifications | Succinylation at Lys-81, adjacent to a coenzyme A binding site. Desuccinylated by SIRT5. |
| Function | Mitochondrial fatty acid beta-oxidation enzyme that catalyzes the third step of the beta-oxidation cycle for medium and short-chain 3-hydroxy fatty acyl-CoAs (C4 to C10). Plays a role in the control of insulin secretion by inhibiting the activation of glutamate dehydrogenase 1 (GLUD1), an enzyme that has an important role in regulating amino acid-induced insulin secretion. |
| Protein Name | Hydroxyacyl-Coenzyme A Dehydrogenase - MitochondrialHcdhMedium And Short-Chain L-3-Hydroxyacyl-Coenzyme A DehydrogenaseShort-Chain 3-Hydroxyacyl-Coa Dehydrogenase |
| Database Links | Reactome: R-HSA-77310Reactome: R-HSA-77346Reactome: R-HSA-77348Reactome: R-HSA-77350Reactome: R-HSA-77352 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Hydroxyacyl-Coenzyme A Dehydrogenase - Mitochondrial antibodyAnti-Hcdh antibodyAnti-Medium And Short-Chain L-3-Hydroxyacyl-Coenzyme A Dehydrogenase antibodyAnti-Short-Chain 3-Hydroxyacyl-Coa Dehydrogenase antibodyAnti-HADH antibodyAnti-HAD antibodyAnti-HAD1 antibodyAnti-HADHSC antibodyAnti-SCHAD antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
