• Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-HACL1 antibody (323-373 aa) (STJ196113)

SKU:
STJ196113

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-2-hydroxyacyl-CoA lyase 1 (323-373 aa) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: HACL1
Gene ID: 26061
Uniprot ID: HACL1_HUMAN
Immunogen Region: 323-373 aa
Specificity: This antibody detects endogenous levels of HACL1 at Human/Mouse/Rat
Immunogen: Synthesized peptide derived from the human HACL1 at the amino acid range 323-373
Function Peroxisomal 2-OH acyl-CoA lyase involved in the cleavage (C1 removal) reaction in the fatty acid alpha-oxydation in a thiamine pyrophosphate (TPP)-dependent manner. Involved in the degradation of 3-methyl-branched fatty acids like phytanic acid and the shortening of 2-hydroxy long-chain fatty acids. Plays a significant role in the biosynthesis of heptadecanal in the liver.
Protein Name 2-Hydroxyacyl-Coa Lyase 1
2-Hydroxyphytanoyl-Coa Lyase
2-Hpcl
Phytanoyl-Coa 2-Hydroxylase 2
Database Links Reactome: R-HSA-389599
Reactome: R-HSA-9033241
Cellular Localisation Peroxisome
Alternative Antibody Names Anti-2-Hydroxyacyl-Coa Lyase 1 antibody
Anti-2-Hydroxyphytanoyl-Coa Lyase antibody
Anti-2-Hpcl antibody
Anti-Phytanoyl-Coa 2-Hydroxylase 2 antibody
Anti-HACL1 antibody
Anti-HPCL antibody
Anti-HPCL2 antibody
Anti-PHYH2 antibody
Anti-HSPC279 antibody

Information sourced from Uniprot.org

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