| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Very-long-chain-3-hydroxyacyl-CoA dehydratase 3 (255-305 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
HACD3 |
| Gene ID: |
51495 |
| Uniprot ID: |
HACD3_HUMAN |
| Immunogen Region: |
255-305 aa |
| Specificity: |
This antibody detects endogenous levels of HACD3 at Human/Mouse |
| Immunogen: |
Synthesized peptide derived from the human HACD3 at the amino acid range 255-305 |
| Function | Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. May be involved in Rac1-signaling pathways leading to the modulation of gene expression. Promotes insulin receptor/INSR autophosphorylation and is involved in INSR internalization. |
| Protein Name | Very-Long-Chain3r-3-Hydroxyacyl-Coa Dehydratase 33-Hydroxyacyl-Coa Dehydratase 3Hacd3Butyrate-Induced Protein 1B-Ind1Hb-Ind1Protein-Tyrosine Phosphatase-Like A Domain-Containing Protein 1 |
| Database Links | Reactome: R-HSA-75876 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Very-Long-Chain antibodyAnti-3r-3-Hydroxyacyl-Coa Dehydratase 3 antibodyAnti-3-Hydroxyacyl-Coa Dehydratase 3 antibodyAnti-Hacd3 antibodyAnti-Butyrate-Induced Protein 1 antibodyAnti-B-Ind1 antibodyAnti-Hb-Ind1 antibodyAnti-Protein-Tyrosine Phosphatase-Like A Domain-Containing Protein 1 antibodyAnti-HACD3 antibodyAnti-BIND1 antibodyAnti-PTPLAD1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
