Anti-HABP2 antibody (270-350 aa) (STJ90086)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from HABP2 at the amino acid range 270-350
General Information
| Short Description | Rabbit polyclonal anti-Hyaluronan-binding protein 2 (270-350 aa) for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:5000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HABP2 |
| Gene ID | 3026 |
| Uniprot ID | HABP2_HUMAN |
| Immunogen | Synthesized peptide derived from HABP2 at the amino acid range 270-350 |
| Immunogen Region | 270-350 aa |
| Specificity | HABP2 Polyclonal Antibody detects endogenous levels of HABP2 protein. |
Additional Info
| Post Translational Modifications | Proteolytic cleavage at Gly-23 or Met-27 can give rise to the 50 kDa heavy chain (HC) and cleavage at Arg-313 or Lys-319 can give rise to the 27 kDa light chain (LC). The HC can undergo further proteolytic cleavage giving rise to a 26 kDa fragment. The LC can undergo further proteolytic cleavage at Arg-313 leading to a 17-kDa fragment and at Arg-480 leading to a 8-kDa fragment. |
| Function | Cleaves the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54' but not the gamma-chain of fibrinogen and therefore does not initiate the formation of the fibrin clot and does not cause the fibrinolysis directly. It does not cleave (activate) prothrombin and plasminogen but converts the inactive single chain urinary plasminogen activator (pro-urokinase) to the active two chain form. Activates coagulation factor VII (Probable). May function as a tumor suppressor negatively regulating cell proliferation and cell migration. |
| Protein Name | Factor Vii-Activating ProteaseFsapFvii ActivatorHepatocyte Growth Factor Activator-Like ProteinHyaluronan-Binding Protein 2Plasma Hyaluronan-Binding ProteinPhbpPlasma Hyaluronan-Binding Serine ProteasePhbsp Cleaved Into - Factor Vii-Activating Protease 50 Kda N-Terminal Heavy Chain - Factor Vii-Activating Protease 50 Kda N-Terminal Heavy Chain Alternate Form - Factor Vii-Activating Protease 27 Kda C-Terminal Light Chain - Factor Vii-Activating Protease 27 Kda C-Terminal Light Chain Alternate Form |
| Database Links | |
| Cellular Localisation | SecretedSecreted As An Inactive Single-Chain Precursor And Is Then Activated To A Heterodimeric Form |
| Alternative Antibody Names | Anti-Factor Vii-Activating Protease antibodyAnti-Fsap antibodyAnti-Fvii Activator antibodyAnti-Hepatocyte Growth Factor Activator-Like Protein antibodyAnti-Hyaluronan-Binding Protein 2 antibodyAnti-Plasma Hyaluronan-Binding Protein antibodyAnti-Phbp antibodyAnti-Plasma Hyaluronan-Binding Serine Protease antibodyAnti-Phbsp Cleaved Into - Factor Vii-Activating Protease 50 Kda N-Terminal Heavy Chain - Factor Vii-Activating Protease 50 Kda N-Terminal Heavy Chain Alternate Form - Factor Vii-Activating Protease 27 Kda C-Terminal Light Chain - Factor Vii-Activating Protease 27 Kda C-Terminal Light Chain Alternate Form antibodyAnti-HABP2 antibodyAnti-HGFAL antibody |
Information sourced from Uniprot.org