Anti-H2BC20P antibody (82-132 aa) (STJ197684)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human H2B2C at the amino acid range 82-132
General Information
| Short Description | Rabbit polyclonal anti-Putative histone H2B type 2-C (82-132 aa) for use in WB in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | H2BC20PUniprot ID=H2B2C_HUMAN" |
| Immunogen | Synthesized peptide derived from the human H2B2C at the amino acid range 82-132 |
| Immunogen Region | 82-132 aa |
| Specificity | This antibody detects endogenous levels of human H2B2C |
Additional Info
| Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| Protein Name | Putative Histone H2b Type 2-CH2b-Clustered Histone 20 PseudogeneHistone H2b.tH2b/T |
| Cellular Localisation | NucleusChromosome |
| Alternative Antibody Names | Anti-Putative Histone H2b Type 2-C antibodyAnti-H2b-Clustered Histone 20 Pseudogene antibodyAnti-Histone H2b.t antibodyAnti-H2b/T antibodyAnti-H2BC20P antibodyAnti-HIST2H2BC antibody |
Information sourced from Uniprot.org