Anti-H2AC18; H2AC19 antibody (STJA0008100)

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	H2AC18.H2AC19
Gene ID:	723790/8337
Uniprot ID:	H2A2A_HUMAN
Specificity:	This antibody detects endogenous levels of HIST2H2AA4 at Human, Mouse, Rat
Immunogen:	Synthesized peptide derived from human HIST2H2AA4

Function	Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Protein Name	Histone H2a Type 2-A H2a-Clustered Histone 18 H2a-Clustered Histone 19 Histone H2a.2 Histone H2a/O
Database Links	Reactome: R-HSA-110328 Reactome: R-HSA-110329 Reactome: R-HSA-110330 Reactome: R-HSA-110331 Reactome: R-HSA-1221632 Reactome: R-HSA-171306 Reactome: R-HSA-1912408 Reactome: R-HSA-201722 Reactome: R-HSA-212300 Reactome: R-HSA-2299718 Reactome: R-HSA-2559580 Reactome: R-HSA-2559582 Reactome: R-HSA-2559586 Reactome: R-HSA-3214815 Reactome: R-HSA-3214847 Reactome: R-HSA-3214858 Reactome: R-HSA-427359 Reactome: R-HSA-427389 Reactome: R-HSA-427413 Reactome: R-HSA-5250924 Reactome: R-HSA-5334118 Reactome: R-HSA-5578749 Reactome: R-HSA-5617472 Reactome: R-HSA-5625886 Reactome: R-HSA-5689603 Reactome: R-HSA-5689880 Reactome: R-HSA-5689901 Reactome: R-HSA-606279 Reactome: R-HSA-68616 Reactome: R-HSA-73728 Reactome: R-HSA-73772 Reactome: R-HSA-8936459 Reactome: R-HSA-8939236 Reactome: R-HSA-9018519 Reactome: R-HSA-912446 Reactome: R-HSA-9609690 Reactome: R-HSA-9610379 Reactome: R-HSA-9616222 Reactome: R-HSA-9670095 Reactome: R-HSA-9710421 Reactome: R-HSA-977225
Cellular Localisation	Nucleus Chromosome
Alternative Antibody Names	Anti-Histone H2a Type 2-A antibody Anti-H2a-Clustered Histone 18 antibody Anti-H2a-Clustered Histone 19 antibody Anti-Histone H2a.2 antibody Anti-Histone H2a/O antibody Anti-H2AC18 antibody Anti-H2AFO antibody Anti-HIST2H2AA antibody Anti-HIST2H2AA3.H2AC19 antibody Anti-HIST2H2AA4 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance