Anti-H2-Ab1 antibody (30-219) (STJ11100586)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
STJ11100586
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General Information

Short DescriptionRabbit polyclonal H2-Ab1 (30-219) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/IHC-P/IF/ICC/ELISA
HostRabbit
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
ConcentrationLot specific
PurificationAffinity purification
Dilution RangeWB:1:500-1:1000
IHC-P:1:50-1:200
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
FormulationPBS with 0.09% Sodium Azide, 50% Glycerol, pH7.3.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolH2-Ab1Uniprot ID=HB2S_MOUSE"
Immunogen Region30-219
Immunogen SequenceSERHFVYQFMGECYFTNGTQ RIRYVTRYIYNREEYVRYDS DVGEHRAVTELGRPDAEYWN SQPEILERTRAELDTVCRHN YEGPETHTSLRRLEQPNVVI SLSRTEALNHHNTLVCSVTD FYPAKIKVRWFRNGQEETVG VSSTQLIRNGDWTFQVLVML EMTPRRGEVYTCHVEHPSLK SPITVEWRAQ
SpecificityRecombinant fusion protein containing a sequence corresponding to amino acids 30-219 of mouse H2-Ab1 (NP_996988.2).

Additional Info

Post Translational Modifications Ubiquitinated in immature dendritic cells leading to down-regulation of MHC class II.
Protein Name H-2 Class Ii Histocompatibility Antigen - A-S Beta Chain
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-H-2 Class Ii Histocompatibility Antigen - A-S Beta Chain antibody
Anti-H2-Ab1 antibody

Information sourced from Uniprot.org

Citations

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