| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-GYPC (1-128) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GYPC |
| Gene ID: |
2995 |
| Uniprot ID: |
GLPC_HUMAN |
| Immunogen Region: |
1-128 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-128 of human Glycophorin C (Glycophorin C (GYPC) ) (NP_002092.1). |
| Immunogen Sequence: |
MWSTRSPNSTAWPLSLEPDP GMASASTTMHTTTIAEPDPG MSGWPDGRMETSTPTIMDIV VIAGVIAAVAIVLVSLLFVM LRYMYRHKGTYHTNEAKGTE FAESADAALQGDPALQDAGD SSRKEYFI |
| Tissue Specificity | Glycophorin-C is expressed in erythrocytes. Glycophorin-D and IsoGPC are ubiquitously expressed. |
| Post Translational Modifications | O-glycosylated with core 1 or possibly core 8 glycans. |
| Function | This protein is a minor sialoglycoprotein in human erythrocyte membranes. The blood group Gerbich antigens and receptors for Plasmodium falciparum merozoites are most likely located within the extracellular domain. Glycophorin-C plays an important role in regulating the stability of red cells. |
| Protein Name | Glycophorin-CGlycoconnectinGlycophorin-DGpdGlycoprotein BetaPas-2'Sialoglycoprotein DCd Antigen Cd236 |
| Database Links | Reactome: R-HSA-202733 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Iii Membrane ProteinLinked To The Membrane Via Band 41 |
| Alternative Antibody Names | Anti-Glycophorin-C antibodyAnti-Glycoconnectin antibodyAnti-Glycophorin-D antibodyAnti-Gpd antibodyAnti-Glycoprotein Beta antibodyAnti-Pas-2' antibodyAnti-Sialoglycoprotein D antibodyAnti-Cd Antigen Cd236 antibodyAnti-GYPC antibodyAnti-GLPC antibodyAnti-GPC antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and Histone H2A. Z knockout (KO) 293T cells, using [KO Validated] Histone H2A. Z Rabbit polyclonal antibody (STJ114316) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/93438/374520/STJ114316_1__91357.1713141034.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and Histone H2A. Z knockout (KO) 293T cells, using [KO Validated] Histone H2A. Z Rabbit polyclonal antibody (STJ114316) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")