Anti-GYPC antibody (1-128) (STJ23898)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal GYPC (1-128) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GYPC |
| Gene ID | 2995 |
| Uniprot ID | GLPC_HUMAN |
| Immunogen Region | 1-128 |
| Immunogen Sequence | MWSTRSPNSTAWPLSLEPDP GMASASTTMHTTTIAEPDPG MSGWPDGRMETSTPTIMDIV VIAGVIAAVAIVLVSLLFVM LRYMYRHKGTYHTNEAKGTE FAESADAALQGDPALQDAGD SSRKEYFI |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-128 of human Glycophorin C (Glycophorin C (GYPC) ) (NP_002092.1). |
Additional Info
| Tissue Specificity | Glycophorin-C is expressed in erythrocytes. Glycophorin-D and IsoGPC are ubiquitously expressed. |
| Post Translational Modifications | O-glycosylated with core 1 or possibly core 8 glycans. |
| Function | This protein is a minor sialoglycoprotein in human erythrocyte membranes. The blood group Gerbich antigens and receptors for Plasmodium falciparum merozoites are most likely located within the extracellular domain. Glycophorin-C plays an important role in regulating the stability of red cells. |
| Protein Name | Glycophorin-CGlycoconnectinGlycophorin-DGpdGlycoprotein BetaPas-2'Sialoglycoprotein DCd Antigen Cd236 |
| Database Links | Reactome: R-HSA-202733 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Iii Membrane ProteinLinked To The Membrane Via Band 41 |
| Alternative Antibody Names | Anti-Glycophorin-C antibodyAnti-Glycoconnectin antibodyAnti-Glycophorin-D antibodyAnti-Gpd antibodyAnti-Glycoprotein Beta antibodyAnti-Pas-2' antibodyAnti-Sialoglycoprotein D antibodyAnti-Cd Antigen Cd236 antibodyAnti-GYPC antibodyAnti-GLPC antibodyAnti-GPC antibody |
Information sourced from Uniprot.org