Anti-GYG1 antibody (234-333) (STJ112256)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal GYG1 (234-333) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GYG1 |
| Gene ID | 2992 |
| Uniprot ID | GLYG_HUMAN |
| Immunogen Region | 234-333 |
| Immunogen Sequence | EAHDPNMTHPEFLILWWNIF TTNVLPLLQQFGLVKDTCSY VNVEDVSGAISHLSLGEIPA MAQPFVSSEERKERWEQGQA DYMGADSFDNIKRKLDTYLQ |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 234-333 of human GYG1 (NP_001171649.1). |
Additional Info
| Tissue Specificity | Highly expressed in skeletal muscle and heart, with lower levels in brain, lung, kidney and pancreas. |
| Post Translational Modifications | Self-glycosylated by the transfer of glucose residues from UDP-glucose to itself, forming an alpha-1,4-glycan of around 10 residues attached to Tyr-195. Phosphorylated. |
| Function | Glycogenin participates in the glycogen biosynthetic process along with glycogen synthase and glycogen branching enzyme. It catalyzes the formation of a short alpha (1,4)-glucosyl chain covalently attached via a glucose 1-O-tyrosyl linkage to internal tyrosine residues and these chains act as primers for the elongation reaction catalyzed by glycogen synthase. |
| Protein Name | Glycogenin-1Gn-1Gn1 |
| Database Links | Reactome: R-HSA-3322077Reactome: R-HSA-3785653Reactome: R-HSA-3814836Reactome: R-HSA-3828062Reactome: R-HSA-5357609Reactome: R-HSA-6798695Reactome: R-HSA-70221 |
| Cellular Localisation | CytoplasmNucleusLocalizes To Glycogen Granules (Glycosomes) In The CytoplasmCytosolic Localization Is Dependent On The Actin Cytoskeleton |
| Alternative Antibody Names | Anti-Glycogenin-1 antibodyAnti-Gn-1 antibodyAnti-Gn1 antibodyAnti-GYG1 antibodyAnti-GYG antibody |
Information sourced from Uniprot.org