| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GYG1 |
| Gene ID: | 2992 |
| Uniprot ID: | GLYG_HUMAN |
| Immunogen Region: | 234-333 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 234-333 of human GYG1 (NP_001171649.1). |
| Immunogen Sequence: | EAHDPNMTHPEFLILWWNIF TTNVLPLLQQFGLVKDTCSY VNVEDVSGAISHLSLGEIPA MAQPFVSSEERKERWEQGQA DYMGADSFDNIKRKLDTYLQ |
| Tissue Specificity | Highly expressed in skeletal muscle and heart, with lower levels in brain, lung, kidney and pancreas. |
| Post Translational Modifications | Self-glycosylated by the transfer of glucose residues from UDP-glucose to itself, forming an alpha-1,4-glycan of around 10 residues attached to Tyr-195. Phosphorylated. |
| Function | Glycogenin participates in the glycogen biosynthetic process along with glycogen synthase and glycogen branching enzyme. It catalyzes the formation of a short alpha (1,4)-glucosyl chain covalently attached via a glucose 1-O-tyrosyl linkage to internal tyrosine residues and these chains act as primers for the elongation reaction catalyzed by glycogen synthase. |
| Protein Name | Glycogenin-1Gn-1Gn1 |
| Database Links | Reactome: R-HSA-3322077Reactome: R-HSA-3785653Reactome: R-HSA-3814836Reactome: R-HSA-3828062Reactome: R-HSA-5357609Reactome: R-HSA-6798695Reactome: R-HSA-70221 |
| Cellular Localisation | CytoplasmNucleusLocalizes To Glycogen Granules (Glycosomes) In The CytoplasmCytosolic Localization Is Dependent On The Actin Cytoskeleton |
| Alternative Antibody Names | Anti-Glycogenin-1 antibodyAnti-Gn-1 antibodyAnti-Gn1 antibodyAnti-GYG1 antibodyAnti-GYG antibody |
Information sourced from Uniprot.org
