Anti-GUCY1A2 antibody (604-654 aa) (STJ198157)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human GCYA2 at the amino acid range 604-654
General Information
| Short Description | Rabbit polyclonal anti-Guanylate cyclase soluble subunit alpha-2 (604-654 aa) for use in WB in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GUCY1A2 |
| Gene ID | 2977 |
| Uniprot ID | GCYA2_HUMAN |
| Immunogen | Synthesized peptide derived from the human GCYA2 at the amino acid range 604-654 |
| Immunogen Region | 604-654 aa |
| Specificity | This antibody detects endogenous levels of human GCYA2 |
Additional Info
| Function | Has guanylyl cyclase on binding to the beta-1 subunit. Isoform 2 acts as a negative regulator of guanylyl cyclase activity as it forms non-functional heterodimers with the beta subunits. |
| Protein Name | Guanylate Cyclase Soluble Subunit Alpha-2Gcs-Alpha-2 |
| Database Links | Reactome: R-HSA-392154Reactome: R-HSA-445355 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Guanylate Cyclase Soluble Subunit Alpha-2 antibodyAnti-Gcs-Alpha-2 antibodyAnti-GUCY1A2 antibodyAnti-GUC1A2 antibodyAnti-GUCSA2 antibody |
Information sourced from Uniprot.org