Anti-GUCA2A antibody (22-115) (STJ111862)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal GUCA2A (22-115) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GUCA2A |
| Gene ID | 2980 |
| Uniprot ID | GUC2A_HUMAN |
| Immunogen Region | 22-115 |
| Immunogen Sequence | VTVQDGNFSFSLESVKKLKD LQEPQEPRVGKLRNFAPIPG EPVVPILCSNPNFPEELKPL CKEPNAQEILQRLEEIAEDP GTCEICAYAACTGC |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 22-115 of human GUCA2A (NP_291031.2). |
Additional Info
| Tissue Specificity | Highly expressed in ileum and colon. Found in plasma. |
| Function | Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. |
| Protein Name | GuanylinGuanylate Cyclase Activator 2aGuanylate Cyclase-Activating Protein 1Guanylate Cyclase-Activating Protein IGcap-I Cleaved Into - Hmw-Guanylin - Guanylin |
| Database Links | Reactome: R-HSA-8935690 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Guanylin antibodyAnti-Guanylate Cyclase Activator 2a antibodyAnti-Guanylate Cyclase-Activating Protein 1 antibodyAnti-Guanylate Cyclase-Activating Protein I antibodyAnti-Gcap-I Cleaved Into - Hmw-Guanylin - Guanylin antibodyAnti-GUCA2A antibodyAnti-GUCA2 antibody |
Information sourced from Uniprot.org