Anti-GTF2E2 antibody (1-291) (STJ111392)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal GTF2E2 (1-291) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GTF2E2 |
| Gene ID | 2961 |
| Uniprot ID | T2EB_HUMAN |
| Immunogen Region | 1-291 |
| Immunogen Sequence | MDPSLLRERELFKKRALSTP VVEKRSASSESSSSSSKKKK TKVEHGGSSGSKQNSDHSNG SFNLKALSGSSGYKFGVLAK IVNYMKTRHQRGDTHPLTLD EILDETQHLDIGLKQKQWLM TEALVNNPKIEVIDGKYAFK PKYNVRDKKALLRLLDQHDQ RGLGGILLEDIEEALPNSQK AVKALGDQILFVNRPDKKKI LFFNDKSCQFSVDEEFQKLW RSVTVDSMDEEKIEEYLKR |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-291 of human GTF2E2 (NP_002086.1). |
Additional Info
| Function | Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. |
| Protein Name | Transcription Initiation Factor Iie Subunit BetaTfiie-BetaGeneral Transcription Factor Iie Subunit 2 |
| Database Links | Reactome: R-HSA-167161Reactome: R-HSA-167162Reactome: R-HSA-167172Reactome: R-HSA-674695Reactome: R-HSA-6807505Reactome: R-HSA-73776Reactome: R-HSA-73779Reactome: R-HSA-75953Reactome: R-HSA-76042 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Initiation Factor Iie Subunit Beta antibodyAnti-Tfiie-Beta antibodyAnti-General Transcription Factor Iie Subunit 2 antibodyAnti-GTF2E2 antibodyAnti-TF2E2 antibody |
Information sourced from Uniprot.org