| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GSTZ1 |
| Gene ID: | 2954 |
| Uniprot ID: | MAAI_HUMAN |
| Immunogen Region: | 1-216 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-216 of human GSTZ1 (NP_665877.1). |
| Immunogen Sequence: | MQAGKPILYSYFRSSCSWRV RIALALKGIDYETVPINLIK DGGQQFSKDFQALNPMKQVP TLKIDGITIHQSLAIIEYLE EMRPTPRLLPQDPKKRASVR MISDLIAGGIQPLQNLSVLK QVGEEMQLTWAQNAITCGFN ALEQILQSTAGIYCVGDEVT MADLCLVPQVANAERFKVDL TPYPTISSINKRLLVLEAFQ VSHPCRQPDTPTELRA |
| Tissue Specificity | Mostly expressed in liver followed by kidney, skeletal muscle and brain. Also expressed in melanocytes, synovium, placenta, breast and fetal liver and heart. |
| Function | Bifunctional enzyme showing minimal glutathione-conjugating activity with ethacrynic acid and 7-chloro-4-nitrobenz-2-oxa-1,3-diazole and maleylacetoacetate isomerase activity. Has also low glutathione peroxidase activity with T-butyl and cumene hydroperoxides. Is able to catalyze the glutathione dependent oxygenation of dichloroacetic acid to glyoxylic acid. |
| Protein Name | Maleylacetoacetate IsomeraseMaaiGstz1-1Glutathione S-Transferase Zeta 1 |
| Database Links | Reactome: R-HSA-156590Reactome: R-HSA-204174Reactome: R-HSA-8963684 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Maleylacetoacetate Isomerase antibodyAnti-Maai antibodyAnti-Gstz1-1 antibodyAnti-Glutathione S-Transferase Zeta 1 antibodyAnti-GSTZ1 antibodyAnti-MAAI antibody |
Information sourced from Uniprot.org