Anti-GSTT1 antibody (1-240 aa) [S5007RM] (STJ11105007)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Glutathione S-Transferase Theta-1 (1-240 aa) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S5007RM |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:5000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GSTT1 |
| Gene ID | 2952 |
| Uniprot ID | GSTT1_HUMAN |
| Immunogen Region | 1-240 aa |
| Immunogen Sequence | MGLELYLDLLSQPCRAVYIF AKKNDIPFELRIVDLIKGQH LSDAFAQVNPLKKVPALKDG DFTLTESVAILLYLTRKYKV PDYWYPQDLQARARVDEYLA WQHTTLRRSCLRALWHKVMF PVFLGEPVSPQTLAATLAEL DVTLQLLEDKFLQNKAFLTG PHISLADLVAITELMHPVGA GCQVFEGRPKLATWRQRVEA AVGEDLFQEAHEVILKAKDF PPADPTIKQKLMPWVLAMI |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human GSTT1. (NP_000844.2). |
Additional Info
| Tissue Specificity | Found in erythrocyte. Expressed at low levels in liver. In lung, expressed at low levels in club cells and ciliated cells at the alveolar/bronchiolar junction. Absent from epithelial cells of larger bronchioles. |
| Function | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Acts on 1,2-epoxy-3-(4-nitrophenoxy)propane, phenethylisothiocyanate 4-nitrobenzyl chloride and 4-nitrophenethyl bromide. Displays glutathione peroxidase activity with cumene hydroperoxide. |
| Protein Name | Glutathione S-Transferase Theta-1Gst Class-Theta-1Glutathione Transferase T1-1 |
| Database Links | Reactome: R-HSA-156590Reactome: R-HSA-9753281 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Glutathione S-Transferase Theta-1 antibodyAnti-Gst Class-Theta-1 antibodyAnti-Glutathione Transferase T1-1 antibodyAnti-GSTT1 antibody |
Information sourced from Uniprot.org