Anti-GSTM4 antibody (Internal) (STJ73572)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-GSTM4 (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/WB/IHC |
| Host | Goat |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Approx 26kDa band observed in lysates of cell line HeLa and in Rat Lung lysates (calculated MW of 25.6kDa according to Human NP_000841.1 and Rat NP_001019475.1 ). Recommended concentr |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | GSTM4 |
| Gene ID | 2948 |
| Uniprot ID | GSTM4_HUMAN |
| Accession Number | NP_000841.1; NP_671489.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | DVSNQLARVCYSPD |
| Specificity | This antibody is expected to recognize both reported isoforms (NP_000841.1; NP_671489.1). |
Additional Info
| Function | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Catalyzes the conjugation of leukotriene A4 with reduced glutathione (GSH) to form leukotriene C4. Can also catalyze the transfer of a glutathionyl group from glutathione (GSH) to 13(S),14(S)-epoxy-docosahexaenoic acid to form maresin conjugate in tissue regeneration 1 (MCTR1), a bioactive lipid mediator that possess potent anti-inflammatory and proresolving actions. |
| Protein Name | Glutathione S-Transferase Mu 4Gst Class-Mu 4Gst-Mu2Gstm4-4Leukotriene C4 Synthase Gstm4 |
| Database Links | Reactome: R-HSA-156590Reactome: R-HSA-9026762 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Glutathione S-Transferase Mu 4 antibodyAnti-Gst Class-Mu 4 antibodyAnti-Gst-Mu2 antibodyAnti-Gstm4-4 antibodyAnti-Leukotriene C4 Synthase Gstm4 antibodyAnti-GSTM4 antibody |
Information sourced from Uniprot.org