Anti-GSTM4 antibody (1-218) (STJ29570)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal GSTM4 (1-218) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GSTM4 |
| Gene ID | 2948 |
| Uniprot ID | GSTM4_HUMAN |
| Immunogen Region | 1-218 |
| Immunogen Sequence | MSMTLGYWDIRGLAHAIRLL LEYTDSSYEEKKYTMGDAPD YDRSQWLNEKFKLGLDFPNL PYLIDGAHKITQSNAILCYI ARKHNLCGETEEEKIRVDIL ENQAMDVSNQLARVCYSPDF EKLKPEYLEELPTMMQHFSQ FLGKRPWFVGDKITFVDFLA YDVLDLHRIFEPNCLDAFPN LKDFISRFEGLEKISAYMKS SRFLPKPLYTRVAVWGNK |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-218 of human GSTM4 (NP_000841.1). |
Additional Info
| Tissue Specificity | Expressed in a wide variety of tissues. |
| Function | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Catalyzes the conjugation of leukotriene A4 with reduced glutathione (GSH) to form leukotriene C4. Can also catalyze the transfer of a glutathionyl group from glutathione (GSH) to 13(S),14(S)-epoxy-docosahexaenoic acid to form maresin conjugate in tissue regeneration 1 (MCTR1), a bioactive lipid mediator that possess potent anti-inflammatory and proresolving actions. |
| Protein Name | Glutathione S-Transferase Mu 4Gst Class-Mu 4Gst-Mu2Gstm4-4Leukotriene C4 Synthase Gstm4 |
| Database Links | Reactome: R-HSA-156590Reactome: R-HSA-9026762 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Glutathione S-Transferase Mu 4 antibodyAnti-Gst Class-Mu 4 antibodyAnti-Gst-Mu2 antibodyAnti-Gstm4-4 antibodyAnti-Leukotriene C4 Synthase Gstm4 antibodyAnti-GSTM4 antibody |
Information sourced from Uniprot.org