| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-GSTM4 (1-218) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GSTM4 |
| Gene ID: |
2948 |
| Uniprot ID: |
GSTM4_HUMAN |
| Immunogen Region: |
1-218 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-218 of human GSTM4 (NP_000841.1). |
| Immunogen Sequence: |
MSMTLGYWDIRGLAHAIRLL LEYTDSSYEEKKYTMGDAPD YDRSQWLNEKFKLGLDFPNL PYLIDGAHKITQSNAILCYI ARKHNLCGETEEEKIRVDIL ENQAMDVSNQLARVCYSPDF EKLKPEYLEELPTMMQHFSQ FLGKRPWFVGDKITFVDFLA YDVLDLHRIFEPNCLDAFPN LKDFISRFEGLEKISAYMKS SRFLPKPLYTRVAVWGNK |
| Tissue Specificity | Expressed in a wide variety of tissues. |
| Function | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Catalyzes the conjugation of leukotriene A4 with reduced glutathione (GSH) to form leukotriene C4. Can also catalyzes the transfer of a glutathionyl group from glutathione (GSH) to 13(S),14(S)-epoxy-docosahexaenoic acid to form maresin conjugate in tissue regeneration 1 (MCTR1), a bioactive lipid mediator that possess potent anti-inflammatory and proresolving actions. |
| Protein Name | Glutathione S-Transferase Mu 4Gst Class-Mu 4Gst-Mu2Gstm4-4Leukotriene C4 Synthase Gstm4 |
| Database Links | Reactome: R-HSA-156590Reactome: R-HSA-9026762 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Glutathione S-Transferase Mu 4 antibodyAnti-Gst Class-Mu 4 antibodyAnti-Gst-Mu2 antibodyAnti-Gstm4-4 antibodyAnti-Leukotriene C4 Synthase Gstm4 antibodyAnti-GSTM4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
