Anti-GSTM1/GSTM2 antibody (C-Term) (STJ70642)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-GSTM1/GSTM2 (C-Term) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:1000.WB: Approx 26kDa band observed in Human Liver and Human Lung lysates (calculated MW of 25.7kDa according to NP_000552.2, and NP_000839.1). Recommended concentration: 1-3µg/ml. |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | GSTM1 |
| Gene ID | 2944 |
| Uniprot ID | GSTM1_HUMAN |
| Accession Number | NP_000552.2; NP_666533.1; NP_000839.1 |
| Immunogen Region | C-Term |
| Immunogen Sequence | CVFSKMAVWGNK |
| Specificity | This antibody is expected to recognise both reported variants of human GSTM1 protein (NP_000552.2; NP_666533.1) and wil also recognise human GSTM2 protein (NP_000839.1). |
Additional Info
| Function | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). Participates in the formation of novel hepoxilin regioisomers. |
| Protein Name | Glutathione S-Transferase Mu 1Gst Hb Subunit 4Gst Class-Mu 1Gstm1-1Gstm1a-1aGstm1b-1bGth4 |
| Database Links | Reactome: R-HSA-156590Reactome: R-HSA-9748787Reactome: R-HSA-9753281 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Glutathione S-Transferase Mu 1 antibodyAnti-Gst Hb Subunit 4 antibodyAnti-Gst Class-Mu 1 antibodyAnti-Gstm1-1 antibodyAnti-Gstm1a-1a antibodyAnti-Gstm1b-1b antibodyAnti-Gth4 antibodyAnti-GSTM1 antibodyAnti-GST1 antibody |
Information sourced from Uniprot.org