Anti-GSTM1 antibody (1-181) (STJ119590)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal GSTM1 (1-181) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GSTM1 |
| Gene ID | 2944 |
| Uniprot ID | GSTM1_HUMAN |
| Immunogen Region | 1-181 |
| Immunogen Sequence | MPMILGYWDIRGLAHAIRLL LEYTDSSYEEKKYTMGDAPD YDRSQWLNEKFKLGLDFPNL PYLIDGAHKITQSNAILCYI ARKHNLCGETEEEKIRVDIL ENQTMDNHMQLGMICYNPEF EKLKPKYLEELPEKLKLYSE FLGKRPWFAGNKGLEKISAY MKSSRFLPRPVFSKMAVWGN K |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-181 of human GSTM1 (NP_666533.1). |
Additional Info
| Tissue Specificity | Liver (at protein level). |
| Function | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). Participates in the formation of novel hepoxilin regioisomers. |
| Protein Name | Glutathione S-Transferase Mu 1Gst Hb Subunit 4Gst Class-Mu 1Gstm1-1Gstm1a-1aGstm1b-1bGth4 |
| Database Links | Reactome: R-HSA-156590Reactome: R-HSA-9748787Reactome: R-HSA-9753281 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Glutathione S-Transferase Mu 1 antibodyAnti-Gst Hb Subunit 4 antibodyAnti-Gst Class-Mu 1 antibodyAnti-Gstm1-1 antibodyAnti-Gstm1a-1a antibodyAnti-Gstm1b-1b antibodyAnti-Gth4 antibodyAnti-GSTM1 antibodyAnti-GST1 antibody |
Information sourced from Uniprot.org